Sorry for the delay in responding but have been able to follow up a lead and now have a (library) copy of Dwyers 'Lost Dublin' with the image of Littles public house at 106 Cuffe street. (what an indespensible resource, amazing images throughout including many from 1916).
Its a fantastic photograph of the pub seemingly taken just after the rising, with a British (?) soldier standing guard, and clear bullet holes in the walls. Interestingly the premises is signed as the "Winter Garden Palace" with 'Philip Little, Tea and wine importer' signed on the window. I haven't been able to find out anything more using the 'Winter Palace' name but maybe somebody might be able to use this to garner more information on the role of the pub during the week.
It was demolished in 1975.
(Are we allowed to post a scanned image or copyright forbid this?)
Quaxer, regarding the reference in Charles Townshends great account, 'Easter 1916' (Penguin2005). Following an account about the occupation of St.Stephens Green and Leeson street by Liam O'Briain in which houses covering the canal bridge were occupied, Townshend describes how on Monday "Margaret Skinnider appeared in the street below with orders from Mallin for half the force to fall back to the Green, and some while later she returned to order the rest back too. The reason was not clear to O'Briain (or to Laurence Nugent, a roving observer, who noted that 'there was no threat of attack' when the post was evacuated)". This is where the Littles reference describes that "The withdrawal of the ICA men from the pub at the corner of Cuffe st also 'seemed strange' to Nugent; 'their scouting, if any, seemed defective' (Laurence Nugent BMH WS 907)".
Denis didn't evacuate Littles until Thursday so the occupation of the pub was continued long after the canal st post was evacuated. Interestingly, the volunteers at the pub didn't reinforce St.Stephens Green or the College but moved on to Jacobs on Thursday.
Denis