No problem, been an interesting exercise. Shame no record of Sarah at Tilehurst but that's the way it goes sometimes. The fact that William was a labourer would suggest that he'd moved to Tilehurst for work - there were a number of large estates and many large farms there at the time, It's likely that Henry followed him workwise and may also have had to move to where jobs were available.
Tilehurst at William's time was spread about a large area on the top of a hill, there was a focal point around the church but the village with shops developed a couple of miles or so away. The hill dropped away all round Tilehurst and immediately south of the church area was the edge of the escarpment dropping down to the River Kennet valley and the A4 Bath Road connecting London and Bath. A road came up the hill from the Bath Road and went past the church but before it did so it passed the house built in 1739 that I lived in for the first ten years of my life. It was built as an extension to a much older farm house, probably 100-150 years older, and was built specifically to be a local coaching inn call the Fox - the farm was Fox Farm. A cousin spotted a painting of the inn in a local antiques shop on a Sunday morning but when he went there mid morning Monday it had been sold which was a shame as it dated from the era when people were drawn with speech bubbles. Unfortunately the farm and our cottage on the end were pulled down mid 1950s by the local council to make way for a massive council housing estate - another farm house of the same period was also destroyed. Nowadays these would have been listed as apart from parts of the church were the oldest buildings in Tilehurst, luckily I have a photo of it dated early 1900s and a water colour painting painted about 1920 so something for my records.
Very interesting what your DNA results show, part of your question answered at least.
Feel free to come back to me if you want any other info.