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General => Ancestral Family Tree DNA Testing => Topic started by: alfietcs on Thursday 16 June 16 15:30 BST (UK)
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Hi there
I hope this isn't too off topic, but I was wondering if there was any research to find out if there is a genetic link amongst people who are rhesus negative and if it could help with DNA testing and tracing ancestors. Or am I barking up the wrong tree, so to speak?
I did attempt some research about rhesus neg on the interweb, and hastily retreated after finding most of the information to be about being either a descendant of the nephilim, aliens, serpents etc or subject to other alarming claims. I did feel like I should hide in a darkened room and check for fins.
I don't know much about DNA testing, so I do apologise if this is a stupid question, but I did wonder if the two could help establish a link.
best wishes
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I can't be of much help, but had to smile at your post. I am Rhesus negative and also tried to do some research on it and came across those same articles you must have seen. ::) ;D
What I do know is that both my parents were RH neg and so are OH and myself, and both my kids are and my siblings. So you can see why I was interested in doing some research, but it was hard to find anything that didn't sound like aliens landing....
There was a Wikipedia article, I think I googled RH negative blood type, but it was some time ago..
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I can't be of much help, but had to smile at your post. I am Rhesus negative and also tried to do some research on it and came across those same articles you must have seen. ::) ;D
What I do know is that both my parents were RH neg and so are OH and myself, and both my kids are and my siblings. So you can see why I was interested in doing some research, but it was hard to find anything that didn't sound like aliens landing....
There was a Wikipedia article, I think I googled RH negative blood type, but it was some time ago..
Wow, you have alot of RH neg people in your family, I can see why you would want to know more :)
It's alarming what's written out there isn't it?. I had to stop reading the comments underneath!
I only knew I was RH neg when I had my kids. It wasn't until I came across a few things about this blood type in some of the ancestry sites that I realised there was all this other stuff written about it.
I did read that it is most common in Basque people / Iberian Peninsula etc and that's about all I know.
Ahh well....I shall slither off now ;D
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From what I remember reading it is passed down genetically in our DNA and it is only found in a relatively small section of the population.
My mum also only found out about it when she had me, but luckily my dad was RH neg too so none of the complications that can occur were a problem. The same with me, my doc was concerned until OH's RH neg status was confirmed.
I think I may have saved an article or two that made some sense, will have a dig through my bookmarks and see if I can find it.
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Maybe there is a connection to genealogy/researching and being Rhesus Neg as so am I!
Not to be too complex-
Everybody carries two Rhesus parts and inherits one from each parent
To be positive you can receive either two positives [+ and +]
or one of each type or [+ and -]
To be negative you receive a negative part from each parent [- and -]
Two Rhesus Positive [+ and +] parents will only have Rhesus Positive [+ and +] children
Two Rhesus Negative [- and -] parents will only have Rhesus Negative [- and -] children
It takes a combination of parents ([- and -] and [+ and -] or [+ and -] and [+ and -]) for a combination of positive and negative sibling children
Negative mothers who are at risk of having a positive baby must be monitored to ensure that they don't reject the baby as a foreign object in the body and this is more prevalent in second and subsequent pregnancies as anti-bodies are built up against the invasion. Injections to prevent the build up of anti-bodies are usually given after the first positive baby is born.
A blood type/group is a characteristic of specific substances on the surface of red blood cells, the two most important classifications to describe blood types in humans are ABO and the Rhesus factor (Rh factor).
More stats here for whomever is interested! (http://www.etoolsage.com/Chart/Blood_Group_Compatibility_Chart.asp)
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Found that link to the article. Keep meaning to sort my bookmarks, into categories but never seem to get around to it
http://genetics.thetech.org/ask/ask381
It makes it pretty easy to understand without turning us into aliens.
Back to the mothership now ;D
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Maybe there is a connection to genealogy/researching and being Rhesus Neg as so am I!
Not to be too complex-
Everybody carries two Rhesus parts and inherits one from each parent
To be positive you can receive either two positives [+ and +]
or one of each type or [+ and -]
To be negative you receive a negative part from each parent [- and -]
Two Rhesus Positive [+ and +] parents will only have Rhesus Positive [+ and +] children
Two Rhesus Negative [- and -] parents will only have Rhesus Negative [- and -] children
It takes a combination of parents ([- and -] and [+ and -] or [+ and -] and [+ and -]) for a combination of positive and negative sibling children
Negative mothers who are at risk of having a positive baby must be monitored to ensure that they don't reject the baby as a foreign object in the body and this is more prevalent in second and subsequent pregnancies as anti-bodies are built up against the invasion. Injections to prevent the build up of anti-bodies are usually given after the first positive baby is born.
A blood type/group is a characteristic of specific substances on the surface of red blood cells, the two most important classifications to describe blood types in humans are ABO and the Rhesus factor (Rh factor).
More stats here for whomever is interested! (http://www.etoolsage.com/Chart/Blood_Group_Compatibility_Chart.asp)
When you read those stats, its amazing that there are as many of us as there are!
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But we still only make up a small percentage of the population. In the US apparently according to some stats only 15% of the population and 7% world wide.
My mum was O- and was a regular donor until her hypertension meds excluded her....
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http://genetics.thetech.org/ask/ask381
It makes it pretty easy to understand without turning us into aliens.
Thanks for the link, really interesting. I had no idea that we might be protected from toxoplasmosis and that people with sickle cell could have protection from malaria. Fascinating stuff.
Back to the mothership now ;D
Live long and prosper ;D
ps:- got me quotes and bolds all confused...sorry ::)
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My husband and I are both O negative. My Mum and one of her siblings are O positive, I don't know about the others. My sister is AB positive. We wonder what group our father might have been!
I wonder about the Rhesus factor when looking at some of my ancestral families where there are many infant deaths.
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Your dad may have been the RH neg,
I have as well, one ancestor lost almost half of her children just after birth....
Also may have been a factor in miscarriages happening after the birth of the first child.
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My husband and I are both O negative. My Mum and one of her siblings are O positive, I don't know about the others. My sister is AB positive. We wonder what group our father might have been!
I wonder about the Rhesus factor when looking at some of my ancestral families where there are many infant deaths.
Usually, where you find a woman has one child, then all other pregnancies end in miscarriages or stillbirths, it is because of the Rh neg factor. They just didn't know what it was, centuries ago, and blamed it on the wrath of God or some such thing.
Dawn M
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My husband and I are both O negative. My Mum and one of her siblings are O positive, I don't know about the others. My sister is AB positive. We wonder what group our father might have been!
I wonder about the Rhesus factor when looking at some of my ancestral families where there are many infant deaths.
For you to be O- you must have received an O from each parent and a Neg- from each parent
For your sister to be AB+ she has to have an AB (dominant) and a Pos+ (also dominant)
To have the same parents and knowing your Mum is O+ two parts (O and O)
So your Dad must have given your sister the AB;
for you to have been O he must have been AB/O
which means he would have tested as AB blood type
As your sister is Rhesus positive she receive a positive from both at least one parent
however, as you are negative you received a Rhesus negative from both parents
which means they both had one part each [+ and -] so each would test as Rhesus positive
This would make your Dad's type AB+ [AB and O with Rhesus + and -]
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Thank you myluck, that is a very clear explanation - I actually understand!
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As your sister is Rhesus positive she receive a positive from both parents
Shouldn't this be "from at least one parent"?
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As your sister is Rhesus positive she receive a positive from both parents
Shouldn't this be "from at least one parent"?
Thank you avm228 you are correct and I've corrected above - apologies to mgeneas
However it doesn't change the outcome of the calculation as AB+
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I'm a Rh negative too, as was my dad (he gave loads of blood, I was stopped having fainted on the first 2 occasions, despite being perfectly happy to donate!). My husband is a positive so they kept a close eye on me when I was expecting my children, who are both positive.
Dad's grandparents lost 6 babies, at a few days to a few months, from a variety of causes.
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My husband and I are both O negative. My Mum and one of her siblings are O positive, I don't know about the others. My sister is AB positive. We wonder what group our father might have been!
I wonder about the Rhesus factor when looking at some of my ancestral families where there are many infant deaths.
A person with AB blood group inherits an A from one parent and a B from the other parent.
Unless a mutation occurs an O parent wouldn't have an AB child.
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Hi, this is my first post on here, so hope I do everything ok. I just got my results back from Ancestry regarding my DNA and I did wonder about RH Neg too. Funnily enough, the response about origins from the Iberian Peninsular, my DNA from there is 7%. I just said to my hubby, such a small percentage and yet probably the origin of my rhesus negativity. Amazing how complex we are!
NAMES:
Lewis, Burton,
Poyser, Burgum, Halestrap, Blackmore,Wilmot, Hodgkinson
PLACES:
1851 to 1950's Plaistow/Canning Town in West Ham district of London
now moving backwards to Hull, and Blore Staffordshire
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How interesting. Being O- I had a special injection within 24 hours of O+ sons arrival.
Have always been interested in the theory of alien life, not keen on reptiles so I will accept being descended from aliens or Gods. ;D ;D ;D ;D
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Even though both OH and I are RH- I was given an injection within hours of son's birth as a precaution. Didn't though for second one. Both children are RH-
Also not so keen on the reptile thing but also having an interest in the concept of alien life, them and gods are certainly more appealing as ancestors....... ;D ;D
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I'm Rhesus A Neg, my husband is B positive, yet all our children are Rh Negative. Some are A, some AB and some O (we have 5 children), so they must all have picked up my husband's negative gene. Oddly my parents both had the same type of blood, they carried brown cards because they were both unusual in that they were positive to give, but negative to receive. I don't know what my brothers blood groups are (in any case one died when he was only 37) but somehow I ended up with Rh Neg blood. When I worked in a hospital I asked a haematologist to explain it to me - of course it's much more complicated than mylucky's very clear explanation. I know if I'm A neg, then my blood group is AO and my husband B pos is BO and our children are mix and match but all got my husband's neg gene.
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Lizzie, did the pathologist explain how, if your husband is Positive, his children get a negative gene from him? Wouldn't it have come from yourself?
??? ??? ??? ???
Dawn M
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My father's family virtually all died at a relatively young age, my aunt being the exception (she lived past 70). When starting out on my family history, I was told that this was because my grandparents had incompatible blood types, rhesus positive and negative.
It's interesting to see that it is very common in northern Spain, as that is where my paternal ancestors came from, several hundred years ago. It could also account for a lack of surviving large families in the line
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Lizzie, did the pathologist explain how, if your husband is Positive, his children get a negative gene from him? Wouldn't it have come from yourself?
??? ??? ??? ???
Dawn M
Dawn I think the explanation is as has been said on here earlier, I must be A(O)-- and my husband B(O)+- so that all the children picked up his negative gene, the eldest is AB neg, one of the others A neg and the others O neg. There's no other explanation as the children (apart from the adopted one) are definitely my children. Likewise I know I am my father's child because I look just like him and his sisters!
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pinefamily - If a husband is Rh positive and mother Rh negative the first baby is generally OK even if it is Rh positive, however it will have produced antibodies to its mother's blood (that's why Rh neg mums are now given an Anti D injection after giving birth). Before the Anti D injection many subsequent babies of these mixed couples picked up the antibodies produced by the first baby and became very ill and many died. It's probably easier if you read up about it, rather than me try to explain in a mangled fashion.
3sillydogs - even though you and your husband are both Rh neg, it's usual to give mum the injection just in case the husband is not the father of the baby ::) My youngest son and his wife are both Rh neg but she had injections after all her 3 children.
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LizzieW... My doc said it was just a precaution but I didn't get it for the second one.....
The RH factor played a part with OH's mum, when he was born all was ok, but the second child born 14months later had issues and was given a blood transfusion. Apparently according to mum when I was born the same procedure was on standby, but because my folks are both neg it wasn't needed, even though I was the first born. They obviously understand the whole thing much better than they did 60 odd years ago....
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Lizzie, did the pathologist explain how, if your husband is Positive, his children get a negative gene from him? Wouldn't it have come from yourself?
??? ??? ??? ???
Dawn M
When it comes to features we inherit genetically we have a genotype and phenotype. Genotype is what your genes are and phenotype is what is expressed.
Rhesus negative gene is what is called recessive and rhesus positive is dominant. This means that:
genotpye - - would be Rhesus negative phenotype but genotype -+ would be rhesus positive phenotype. You inherit one chromosome from each parent so in this case the children inherited the -ve gene from their father.
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Well explained, PharmaT.
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I've been Rhesus neg all my life and never knew any of this. I found out when I gave blood as a student, many moons ago, they said my blood was rare and I should give as often as I could. Mum told me she had to have an injection because 'I had funny blood', when I was born but, I had no idea of the implications.
*wanders off to look for her flying saucer*
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Neli - I think Rh Neg blood is less rare than people originally thought. If you think of all the Rh neg people there were, most of whom had children who were also Rh Neg - in my case 5 children - and at least one of my children married someone with Rh Neg blood, so their 3 children all have Rh Neg, the numbers must be growing.
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It is still fairly uncommon if some of the statistics are to be believed, they say that only about 7% of the world's population is negative.....
Most folk are RH+
http://www.rhnegativeregistry.com/welcome.html
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I'm rhesus negative too...obviously descended from gods and Angels and all that ;)
Am actually expecting my second child too (13 years after my 1st...must be mad lol) and have to have that anti-d injection a bit later on.
My mom isn't rhesus (can't remember what she said she is, a or o??) so must have come from dads line.
Thank god for modern medicine! I remember reading that Queen Anne was probably this blood type too and that was why she had such a tragic child bearing history (18 infant deaths and numerous miscarriages if I remember right).
Lisa X
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Hi everyone.
There have been some really helpful and interesting posts here, I have enjoyed reading them.
I've posted a link below that has some percentages of populations with R Neg blood. Some of the articles on this site need taking with a hefty pinch of salt, but I can see sense in this one:-
http://www.rhesusnegative.net/staynegative/topics/where-is-rh-negative-blood-most-frequent/
I would be very interesting, if at some point down the line, there could be established links proved through DNA and blood grouping etc. It does seem that according to the link that there are pockets of higher frequency R Neg blood which include Basque, Berber and Ireland/Scotland and Australia.
All fascinating stuff anyway.
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Very interesting.
Both my parents were A Rh neg and both were 'Celtic hybrids' - Scots/Welsh/some border English and a touch of Irish in the 18C on both sides!. My sister and I were/are also A Rh neg ::)
During WW2, my Dad was asked to give blood very frequently as he was told he had useful blood!
I've later discovered that my late sister, niece and I also have Factor V Liden - a clotting factor.
Gadget
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My Mum was Rhesus D Neg and the only problem she had was when my Brother was born...he had to have a blood change...she called him a "Blue Baby" ???
Carol
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I'm AB Rhesus negative - can trace my ancestors back to mid 18th century, and all from Yorkshire.
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My Mum was Rhesus D Neg and the only problem she had was when my Brother was born...he had to have a blood change...she called him a "Blue Baby" ???
Carol
My OH's mother had the same issue with her second child but not with the 3rd they said because there was a 8 year gap between the 2nd and 3rd.
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I doubt having an 8 year gap would make a difference, it's possible that the 3rd baby was Rh Neg or that by the time the 2nd one was born, although he was a "blue baby", the anti-D vaccine was available and mum was given that.
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Well that's what she said anyway, but then who knows, all I do know is she went on about the 2nd one being a "blue baby" because of her blood. OH is RHneg not sure about the other kids
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If you OH is Rh Neg, then the chances are baby number 3 was also Rh Neg, so didn't have any problems.
I had a baby adopted in 1960 and I've just sent her an e-mail to ask what her blood group is (we got back in touch about 15 years ago). If she has Rh+ blood it could have caused problems with the children I had later if I hadn't been fortunate enough to have a husband who obviously has both positive and negative genotypes. (See pharmaT's post for explanation). The Anti-D vaccine wasn't available until after I'd had my 4th child in 1968 and when I had the 5th in 1974 his blood was tested and found to be Rh- so I didn't need the vaccine. I've since found out all the children with my husband are Rh negative.
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I'm rhesus negative too...obviously descended from gods and Angels and all that ;)
Am actually expecting my second child too (13 years after my 1st...must be mad lol) and have to have that anti-d injection a bit later on.
My mom isn't rhesus (can't remember what she said she is, a or o??) so must have come from dads line.
Thank god for modern medicine! I remember reading that Queen Anne was probably this blood type too and that was why she had such a tragic child bearing history (18 infant deaths and numerous miscarriages if I remember right).
Lisa X
Everybody is either rhesus positive or negative and everybody is either O,A,B or AB. For example I'm A positive and my husband is OK positive. Overall the most common blood group is O positive. O negative is the universal donor meaning any one can have O neg blood in an emergency. AB positive is the universal acceptor and can safely get any blood in an emergency although fully cross matched is always preferable.
The rarest blood group is AB negative due to the combination of genotypes needed and the odds of having a child with that blood group.
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OH is AB neg, me being A neg, I still had the shot after son was born as a precaution but not after my daughter.
I think it is an underlying reason why so many of our ancestors lost children soon after birth or had many miscarriages....
Gods, Angels and Aliens are preferable ancestors than the reptilian ones that some believe we are descended from..... ::) ;D ;D
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I always knew I was unique (well almost) 8)
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OH is AB neg, me being A neg, I still had the shot after son was born as a precaution but not after my daughter.
Time was when they always gave Rh Neg mums the vaccine as they couldn't be sure the husband was actually the father ::) Of course if the baby is Rh Neg, then no vaccine is required so perhaps your daughter has Rh neg blood too.
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Both kids are negative....
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The rarest blood group is AB negative due to the combination of genotypes needed and the odds of having a child with that blood group
My daughter is AB negative, a product of me being A- and my husband B+
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Both kids are negative....
Both kids are negative....
I don't know how old your children are, but I think originally they gave the shot without testing the baby's blood group as a precaution, but now I guess it's cheaper to test the baby's blood group than waste the vaccine on someone who may not need it.
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They tested the kids when they were born so more than likely you're right and that's why I wasn't given the shot the second time around.
My doc said it was only as a precaution the first time...
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I am AB Neg which is the rarest. I have been trying to put together a family tree of blood groups but it's almost impossible as several in the family don't know their group. The two youngest haven't been tested (age 1 and 2). Two of the fathers' groups aren't known. Really annoying that blood group testing isn't done for everyone.
Anyway, here is a little chart which shows how you inherit your blood group.
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I checked with the daughter I had who was adopted and she is also Rh Negative. I have no idea what her father's blood group was.
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Just responding to 3SillyDogs, I read the same article which thankfully did NOT turn us into Reptilian Overloads (Hahaha) or anything crazy like that - however, I did not agree with having the RH factor to be as common as someone having blue eyes or blonde hair, because there are so few of us on the entire planet, that was a terrible analogy... And, the Doctor, geneticist - or whomever wrote the article, got to go back and recheck the credentials - I believe got a "fact" wrong that we are less susceptible to toxoplasmia - the research I've done actually states the opposite, that we being RH negative are actually MORE susceptible to the condition and several videos and articles that I've stumbled upon warn against owning cats due to this... So, I don't know who's right at this point, all I know is that I am certainly not a "reptile" and if I did come from E.T. I would say "Beam me up Scotty, it sucks down here!" LOL I think we are a "mutation" - never thought I'd be saying I'm happy to be a mutant! 😂 But, yeah... I mean there COULD be some ancient astronaut genetic manipulation going on, just for the plain sake that our blood type is so odd that I cannot "mate" with another human being who is not RH positive without the RHOGAM shot, but still seems too 'exotic' for me to seriously buy into... Much love out to my "mutant" brothers and sisters - peace - L.
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I know I'm assisting in thread necromancy here but it was an interesting topic to read anyway.
My parents are A- and O+ with my older brother being A+ (Rhesus conflict with mum). When I was born I tested O- but when I became a blood donor it returned as O+.
It does make me wonder how many of my ancestors had a rhesus problem. I can think of one or two who had one or a couple of children and then nothing, or had childless marriages, but not so much ones that had one child healthy and then lost subsequent ones where any records survive to notify me. Then again, one of my families where I always wondered why there was only one child was JONES mmn EVAN in Wales, so heh.
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I know I'm assisting in thread necromancy here but it was an interesting topic to read anyway.
My parents are A- and O+ with my older brother being A+ (Rhesus conflict with mum). When I was born I tested O- but when I became a blood donor it returned as O+.
It does make me wonder how many of my ancestors had a rhesus problem. I can think of one or two who had one or a couple of children and then nothing, or had childless marriages, but not so much ones that had one child healthy and then lost subsequent ones where any records survive to notify me. Then again, one of my families where I always wondered why there was only one child was JONES mmn EVAN in Wales, so heh.
Having one healthy child then no more is very common when the mother is rhesus negative. If the first child is rhesus positive it is fine while in the womb. The mother does not get exposed to the baby's antigens until the point of birth. At this point the mother will start to produce antibodies against the rhesus positive affecting subsequent pregnancies.
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Lewis, the rhesus blood groups are more complicated than you think. For instance as we all have equal numbers of genes from our parents, we also have equal numbers of rhesus factors from them. My parents were both rh neg for receiving blood but positive and to give, probably similar to Ayashi on here, however I am Rh A neg, meaning I got 2 rhesus factors from my parents. So I am Rh - -, in the other hand by OH is Rh + - , we know that because all our children are Rh - . I could write pages on this subject but having to type this on my 'phone (laptop out of action) it just takes too long.
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Having read military medical records for some of mine I'd put the single offspring (always conceived if not born within a few months of marriage) down to a certain medical condition. The rhesus factor is something I'd never considered since to the best of my knowledge it's not a problem for current generations.
Jane :-)
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My mother was O positive I do not know the blood group of my father (long deceased)
I am O negative
My sibling is AB positive
Any ideas what our father's blood group might be?
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Sure there are charts online but I can’t find one that i can link to from my phone 🙄
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Mgeneas, pamela21's reply #49 has a chart that may help you. Just remember that to have a rhesus negative factor you have inherited negative gene from both parents. The positive gene is dominant and will dominate the negative (a bit like life, there is often a dominant one in a relationship) so you may be rh+ but have a negative, recessive, gene that can be passed on.
My mother never knew her blood type I was born way before testing for pregnant mums was done, but my father was A+ and I am O- so he must have had a negative and a positive gene.
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My mother was O positive I do not know the blood group of my father (long deceased)
I am O negative
My sibling is AB positive
Any ideas what our father's blood group might be?
There is an inhibitor gene which can mask a person's blood type, showing O when tested. The fact that you have a sibling with AB and a mother with O suggests your mother has this inhibitor gene because an O type cannot produce an AB offspring.
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My mother was O positive I do not know the blood group of my father (long deceased)
I am O negative
My sibling is AB positive
Any ideas what our father's blood group might be?
I think you ar mistaken about your mother's blood group. An O parent can not have an AB child. People with the AB bloodgroup get the A from one parent and the B from the other parent.
A and B are both dominant phenotypes over O (so if you have AA or AO your blood group is A, and if you have BB or BO your blood group is B). People with the O bloodgroup must be OO. She'd have neither an A nor a B, so you mother wouldn't have been able to give your sibling the A or the B. She could only give them an O.
ETA - I should have read macwill's response!
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O Positive was on my mother's hospital chart.
Still wondering about my father though! But thanks for all the coments.
As my spouse and I are both O negative does that mean our offspring are too?
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O Positive was on my mother's hospital chart.
Still wondering about my father though! But thanks for all the coments.
As my spouse and I are both O negative does that mean our offspring are too?
Yes your mother's chart would show O+ with the normal test if she had the inhibitor.
Yes your children should be O- , unless you, or your husband, also have the inhibitor.
If you are concerned please discuss it with a professional medical expert.
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As I said earlier, the Rhesus factor is too complicated to discuss on here. I was told, when I found out my blood group (Rh A-) that my parents couldn't be my parents, but they definitely are. I look exactly like my dad and his sisters and my mother definitely remembers giving birth to me!!
I am Rh A- negative and my husband is Rh B+ but all our children are rhesus negative. One is AB-, another is A-, the others are O-negative. In simple terms A group is actually AA or AO, B group is BB or BO but it could be that my group is A-O- whilst my husband's (as our children all have negative blood) must be B-O+ or B+O-, it cannot be BB - in any form - or none of our children would be O- and they are, so despite the fact that positive is supposed to be the dominant factor, there was actually more chance of our children ending up Rh negative which some of them did (we have 5).
Read http://rhnegativeregistry.com/rh_negative_rare_and_basic_blood_types.html for a simple explanation.
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I'm just an A so can't add anything. What a fascinating thread to read , thankyou. I'm sure we have all learned from it. :)
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Slightly off-topic (apologies).
Whilst pregnant my eldest sister was informed she had a rare bloodtype, when she had recovered she was implored to become a donor.
Only one problem, the mere mention/sight of blood sends her queasy and the proximity of a syringe has been known to cause her to faint. :o ;D
Needless to say, she did NOT sign up.
How she survived having three children I will never know! ::) ;D
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Very interesting thread.
Alone out of 3 siblings I have the B- grouping, and had to have the injection after my first son was born in 1978.
I made my first donation when I was 21, in the crypt of St Martin's in the Fields at Trafalgar Square, London, and have been lucky to remain healthy, so continue to be a regular donor.
Apparently only 2% of the doning population are B- group, which can be used for patients in 4 different groups: B-, B+, AB- and AB+ because of the presence of antigen B, and the absence Rh antigen in my blood.
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Hmm. I came across this website while googling DNA and RH - Factor. Someone on here said that it is common along the iberian peninsula and basque people and I've heard this before.
I'm RH- and just did my DNA at ancestry and it says that I am 7% from the iberian peninsula. If anyone on here comes across recent studies about this, please do mention :)
Thanks.
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I had my DNA done by a company called 23andMe, which seems to give slightly different results to Ancestry DNA tests, however it shows I am 2.5% Iberian and 2.8% Southern Europe, also 0.1% Asian where Rh Negative is also common.
Interestingly, I am only 42.2% from British & Irish United Kingdom, and the rest from all over Europe, a little Ashkenazi Jewish (which I had guessed) and a bit of Asian.
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A chap called Stephen Oppenheimer has written a new paperback on then origins of some of us Brits. You can view his presentation on Youtube at:
This is Part 1 and lasts 22m 15s.
https://www.youtube.com/watch?v=JEL7nCM5itg
Part 2 lasts another 22m 58s
https://www.youtube.com/watch?v=vFQiuGvxMd0
The Celts of what is now The Basque Country populated the western fringes of Northern Europe following the end of the last ice age c15,000bp.
There is a brief mention of distribution of blood group B and also Rh -ve alleles. The distributions are not the same and Rh- doesn't share the same distribution/migration as B
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Hi there
I hope this isn't too off topic, but I was wondering if there was any research to find out if there is a genetic link amongst people who are rhesus negative and if it could help with DNA testing and tracing ancestors. Or am I barking up the wrong tree, so to speak?
I did attempt some research about rhesus neg on the interweb, and hastily retreated after finding most of the information to be about being either a descendant of the nephilim, aliens, serpents etc or subject to other alarming claims. I did feel like I should hide in a darkened room and check for fins.
I don't know much about DNA testing, so I do apologise if this is a stupid question, but I did wonder if the two could help establish a link.
best wishes
I am one of those reptilian space aliens. We supposedly often have red hair and green eyes. That explains a lot in my case... ;D (Off to check for fins.)
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I read an article some time ago relating to the frequency of alien visitations to this planet.
The comment was, if there have been so many visits, what is it about this very minor planet, circling a very insignificant star, that has created a veritable crossroad for said aliens.
I doubt that it can be the humans who are supposed to be the dominate species.
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a genetic link amongst people who are rhesus negative and if it could help with DNA testing and tracing ancestors.
Well, your Rhesus factor is determined by your genes but it is unlikely to help you to trace ancestors. It can only eliminate certain parent/child uncertainties and only if you know which Rhesus factor each carries. This would enable you to say when they are not related; two Rh- parents cannot have a Rh+ child.
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two Rh- parents cannot have a Rh+ child.
I guess it's possible if the Rh parents are Rh-/Rh+. In my case my parents were both Rh+ but I turned out to be Rh- and presumably Rh-/Rh- as all my children are Rh-, yet my husband is Rh+ (so probably Rh+/Rh-. When my parents went to become blood donors they were told their blood group meant they were positive to give but negative to receive - and it's interesting that the two of them should meet each other, especially as their near ancestors came from totally different parts of the UK! When I was doing my midwifery training I asked the haematologist lecturer to explain to me how I could be the child of 2 Rh+ parents and it is (and obviously was) possible. People could say I'm not my father's daughter but as I look exactly like him and his sisters, I think I probably am ;)
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two Rh- parents cannot have a Rh+ child.
I guess it's possible if the Rh parents are Rh-/Rh+. In my case my parents were both Rh+ but I turned out to be Rh- and presumably Rh-/Rh- as all my children are Rh-, yet my husband is Rh+ (so probably Rh+/Rh-. When my parents went to become blood donors they were told their blood group meant they were positive to give but negative to receive - and it's interesting that the two of them should meet each other, especially as their near ancestors came from totally different parts of the UK! When I was doing my midwifery training I asked the haematologist lecturer to explain to me how I could be the child of 2 Rh+ parents and it is (and obviously was) possible. People could say I'm not my father's daughter but as I look exactly like him and his sisters, I think I probably am ;)
Two rhesus negative parents cannot have a rhesus positive child as for your phenotype to be rhesus negative your genotype has to be Rh-/Rh- as the Rh negative gene is recessive to the Rh+ gene. A Rhesus positive parent however could have a rhesus negative child if their genotype was Rh+/Rh- providing they had a child with someone who was either Rhesus positive with a RH+/Rh- genotype as well or someone who was Rh- (Rh-/Rh-)
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Pharma - OK, I understand, so if someone has a phenotype Rh+/Rh- they are automatically Rh+ but can have Rh- neg children with someone who also has phenotype Rh+/Rh-, which is what happened in my family. I guess as I am Rh-, so presumably with a phenotype of Rh-/Rh- and as all our children are also Rh-, my husband's phenotype must be Rh+/Rh-. What I don't understand is why my parents were given special donor cards and were told their blood had to be treated as positive when given to someone, but negative if they needed blood. No-one has ever told my husband that, as far as he is concerned his blood group is Rh+. He used to be a blood donor and just had the usual coloured card for RhB+. I used to know which coloured card meant which blood group, but I've forgotten now. All I know is my parents both had brown cards.
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I have posted this on message 49, hopefully it will answer all your questions.
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Thank you Pamela21, it answers some questions.
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When my parents went to become blood donors they were told their blood group meant they were positive to give but negative to receive
Does this not mean that only positive blood groups can receive their blood as they were rh pos, but they could receive negative blood as well as positive. Depending on the blood group I’ve always understood that blood group O is the universal giver but can only receive O blood, and within that every blood group can accept O rh neg but only any positive blood types can receive O rh pos!
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Negative can only receive negative blood, but can donate to positive, group O Rh Neg is a universal donor and can be given to all, but can only receive O Rh Neg blood, as I was given to understand. Mum was ORhNeg and was a regular donor.
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The point is when my parents gave blood it was considered Rh positive so could only be given to someone with Rh positive blood. However, if they ever needed blood themselves they would have to be given Rh negative blood. As far as I can see this must be to do with antigens, not the well known D antigen, but some other antigen.
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The either Rhesus Positive or Rhesus negative is the antigen. The blood type of the person will either have it Rh+ or not Rh- . Those that have it can receive blood from those that don't but not vice versa.
rhesus factor
an antigen occurring on the red blood cells of many humans (around 85 per cent) and some other primates. It is particularly important as a cause of haemolytic disease of the newborn and of incompatibility in blood transfusions.
This explains it quite nicely
https://en.wikipedia.org/wiki/Rh_blood_group_system
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To answer the original question about using blood characteristics for tracing ancestry. Dr. Albert Casey tested thousands of Irish and other Europeans for 15 to 20 characteristics for blood (Rh included). He published a series of large source material books (16 volumes) on his Munster, Ireland ancestry but several volumes have his research on usage of blood characteristics to determine relationships between donors. Unfortunately, there is some Eugenics included as well (skull dimensions). If you want to know how blood characteristics can be used for tracing ancestry, this is a pretty interesting study of blood characteristics done in the 1950s which have a genetic genealogy component. These volumes are located in National Library of Ireland as well as the Hunstville, AL public library (and many other libraries).
These volumes have a lot of genealogical source material for County Cork and Kerry and these blood studies are extremely unique research for pre genetic genealogy research (they are pretty heavy reads and would help to have a good understanding of these blood characteristics):
http://www.worldcat.org/title/okief-coshe-mang-slieve-lougher-and-upper-blackwater-in-ireland/oclc/827660