"Three brothers sailed from England and landed at Georgetown, South Carolina, in the Pee Dee (river) Sections. James had a warrant for 500 acres of land on August 19, 1701. John had a warrant for 500 acres and Stephen had a warrant for 300 acres in 1699."
From Sally's "Warrants for Land in South Carolina".
Georgetown is a bit further north up the coast of SC, and they would have had to travel the river up a bit.

The Lumber River, Little Pee Dee River, Lynches River, and Waccamaw River all converge with the Pee Dee River near Georgetown. A lot of my Ford ancestors are from the area of the Lumber River (Drowning Creek), as well as the surrounding areas. In fact, I grew up in the area between the Lynches and Pee Dee Rivers. Going pretty far back, the family seems to be very agricultural which would have explained why they chose this area to settle. Also, one of them was a magistrate, but I think the records were burned during the Civil War (someone had the foresight to move them from the pathway of the troops that were burning... and unfortunately chose a place that did burn after all).

My ancestor was James (believed to be born about 1660 in England). I have no idea why there are Charleston church records for the son Preserved's family.