There have been Meads there back into the 15th century, as well as in nearby Ilmer and Saunderton, though it’s not possible to be sure about the relationships for the first couple of generations.
First, John Mede of Towersey, husbandman, in the Court of Common Pleas:
1472 Hilary/dorses 1313
Bucks. Thomas Hampden, esq, versus John Mede, of Toursey, husbandman; John Baker, of Toursey, husbandman. Trespass: breach of close at Toursey.
Then, a generation later, William Mede, of Towrsey, husbandmanm in CP:
1501 Easter/dorses 484
Bucks. Nicholas Bonse or Bouse versus Nicholas Brytwell, of Charsley, gent; Richard Hykkes, of Crendon, husbandman; and William Mede of Towrsey, husbandman. Debt.
1503 Trinity/fronts 120
Bucks. Thomas Ingylson versus William Mede, of Toursey, husbandman; John Sprygyns, of Parva Kymbyll, husbandman. Debt.
A generation later, John Mede, of Toursey, husbandman, in CP:
1518 Trinity/dorses 891
Bucks. Thomas Boller versus John Mede, of Toursey, husbandman; Robert, Bayle, of Toursey, husbandman; Thomas Ravenyng, of Toursey, husbandman; William Webbe, of Toursey, husbandman; Thomas Darell, of Toursey, husbandman; Trespass: breach of close.
This must be the same person as in the 1524 lay subsidy and 1522 muster rolls:
1522 musters, John Mede of Towersey Goods £6
1524 lay subsidy John Mede of Towresy £4
William Mede of Towersey Grange, yeoman, is identified as the son of John in Common Pleas:
1550 Michaelmas/fronts b 2113
Bucks. William Fylde and Maude his wife versus John Belson, of Towersey Grange, gent, and William Mede of Towersey Grange, yeoman, son of John Mede, on a plea of covenant.
1552 Hilary/fronts 162
Bucks. William Fylde and Maude his wife versus John Belson, of Towersey Graunge, gent, and William Mede of Towersey Graunge, yeoman, son of John Mede, on a plea of covenant.
I also have some parish records of baptisms and burials, but only starting in the 1590s for Towersey (and ending in 1638):
https://sites.google.com/site/meadfamilyhistory/home/counties/bucks/burialshttps://sites.google.com/site/meadfamilyhistory/home/counties/bucks/baptismsI have wills and other info about Meads nearby, in Ilmer, Saunderton, etc:
https://sites.google.com/site/meadfamilyhistory/home