It's not just you that Edge misbehaves for. Sometimes I get the same effect - at random.
It can have been working fine, then it just seems to ignore holding the Ctrl key when clicking to start a fresh tab. Sometimes, using Ctrl-K to duplicate the current tab gives me a version where Ctrl-click works properly.
I believe that the browser is trying to optimise the data in the wrong sequence when building the page, somehow setting the flag to disable Ctrl-click.
