Author Topic: Intrathecal antibody test  (Read 1081 times)

Offline BushInn1746

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Intrathecal antibody test
« on: Tuesday 19 May 20 05:19 BST (UK) »
UK Government begins large-scale virus infection and antibody test study

https://www.gov.uk/government/news/government-begins-large-scale-virus-infection-and-antibody-test-study

Intrathecal - Introduced into or occurring in the space under the arachnoid membrane of the brain or spinal cord.

https://www.gov.uk/government/publications/intrathecal-antibody-test-request-form

"The flagship study forms part of Pillar 4 of the governmentís COVID-19 testing strategy, to conduct UK-wide surveillance testing to learn more about the spread of the disease and help inform the development of new tests and treatments."
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This is highly Specialised Testing!

It takes me back to my 30s when I had Blood tests, CSF Tests and other Tests to try and discover the reason for Atrophy.

Mark

Online Viktoria

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Re: Intrathecal antibody test
« Reply #1 on: Tuesday 19 May 20 10:40 BST (UK) »
It almost sounds worse than the disease!

Ouch!
Hope it solved the causes your health issues.
Is it very time consuming?
I donít know the latest numbers in America ,I wonder how people manage without a health service like ours.?
Viktoria.



Offline sugarfizzle

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Re: Intrathecal antibody test
« Reply #2 on: Tuesday 19 May 20 11:25 BST (UK) »
I must be missing something, where does it indicate that intra-thecal testing will be used to detect Covid-19 antibodies?

The form linked to indicates that the patient has symptoms of encephalitis, meningitis, or meningo encephalitis.

Lumbar punctures are only done in a hospital setting, as far as I am aware. I certainly would not undergo one just to see if I had antibodies, but if I had suspected brain infection as above, obviously I would have one done.

Regards Margaret
STEER, mainly Surrey, Kent; PINNOCKS/HAINES, Gosport, Hants; BARKER, mainly Broadwater, Sussex; Gosport, Hampshire; LAVERSUCH, Micheldever, Hampshire; WESTALL, London, Reading, Berks; HYDE, Croydon, Surrey; BRIGDEN, Hadlow, Kent and London; TUTHILL/STEPHENS, London
WILKINSON, Leeds, Yorkshire and Liverpool; WILLIAMSON, Liverpool; BEARE, Yeovil, Somerset; ALLEN, Kent and London; GORST, Liverpool; HOYLE, mainly Leeds, Yorkshire

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Offline BushInn1746

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Re: Intrathecal antibody test
« Reply #3 on: Tuesday 19 May 20 12:34 BST (UK) »
I must be missing something, where does it indicate that intra-thecal testing will be used to detect Covid-19 antibodies?

The form linked to indicates that the patient has symptoms of encephalitis, meningitis, or meningo encephalitis.

Lumbar punctures are only done in a hospital setting, as far as I am aware. I certainly would not undergo one just to see if I had antibodies, but if I had suspected brain infection as above, obviously I would have one done.

Regards Margaret

Hi Margaret and Viktoria

Reference to Long Term Covid-19 Study here (report expected about May 2021)
https://www.gov.uk/government/news/government-begins-large-scale-virus-infection-and-antibody-test-study

According to the online Form it suggests two types of tests:-
1. Blood Tests.
2. CSF (which is usually Cerebral Spinal Fluid)

CSF is usually taken by Lumbar Puncture as you say and whilst the needle was in, they took my CSF pressure.

If it helps, taking my CSF sample was absolutely painless.

You lay on your side on the hospital bed and arch your back as much as possible (head toward your toes) and try to relax. (Relaxing is not easy after the dishonest pub stories heard  :D ).

A Local Anesthetic is injected (a normal tiny needle scratch) near to joint gap they have decided to enter. They check the anesthetic has worked first. When happy they then inject with a small needle between the spine joints and into the CSF spinal fluid for a sample.

Despite a scan showing Atrophy and deterioration etc., I'm afraid the CSF never established a cause.

Take care, Mark

Offline sugarfizzle

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Re: Intrathecal antibody test
« Reply #4 on: Tuesday 19 May 20 13:11 BST (UK) »
Atrophy and deterioration - that could explain a lot  :)

I was a nurse for over 40 years, I saw quite a few LPs that didn't go as well as yours did, Mark, though the majority went fairly smoothly.

But the form indicates reasons for the test would only be for serious brain disease, so they would only look for the C-19 antibodies in patients who developed it.

Interesting. There is still so much to learn about this virus.

Regards Margaret
STEER, mainly Surrey, Kent; PINNOCKS/HAINES, Gosport, Hants; BARKER, mainly Broadwater, Sussex; Gosport, Hampshire; LAVERSUCH, Micheldever, Hampshire; WESTALL, London, Reading, Berks; HYDE, Croydon, Surrey; BRIGDEN, Hadlow, Kent and London; TUTHILL/STEPHENS, London
WILKINSON, Leeds, Yorkshire and Liverpool; WILLIAMSON, Liverpool; BEARE, Yeovil, Somerset; ALLEN, Kent and London; GORST, Liverpool; HOYLE, mainly Leeds, Yorkshire

Census Information is Crown Copyright, from www.nationalarchives.go

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Re: Intrathecal antibody test
« Reply #5 on: Tuesday 19 May 20 15:13 BST (UK) »
And what is the bet the darn thing will be changing all the time.,
So no cause known for your Atrophy.?
As I remember Atrophy is a symptom,not an actual disease,but please correct me ,you know more than I do.
Thanks for the info, as has been said, you can learn something almost every day on RootsChat.
Viktoria.
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Offline BushInn1746

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Re: Intrathecal antibody test
« Reply #6 on: Tuesday 19 May 20 20:01 BST (UK) »
Hi

Reading a few bits & pieces (in two of many Medical Reports) and just looking at my Stash of a few Cholesterol ruining baddies (6 packets of biscuits & several packets of chocolate bars acquired throughout Lockdown), I'm personally more concerned about snacking on these  :o  , than going outside for a walk   :) !!

Especially when good diet and exercise is vital to keep my heart & circulation as healthy as possible, keeping my BMI right and to be able to try and fight Coronavirus!

Mark

Offline BushInn1746

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Re: Intrathecal antibody test
« Reply #7 on: Wednesday 20 May 20 18:53 BST (UK) »

The form linked to indicates that the patient has symptoms of encephalitis, meningitis, or meningo encephalitis.

Lumbar punctures are only done in a hospital setting, as far as I am aware. I certainly would not undergo one just to see if I had antibodies, but if I had suspected brain infection as above, obviously I would have one done.

Regards Margaret

Margaret, it was most interesting that you spotted those Brain illnesses on the Form.

Because Coronavirus Covid-19 (including Non-respiratory Covid-19) is also causing inflammation to various organs, including Encephalitis (inflammation in the brain).
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It seems that an opinion is forming that people begin to lose their natural healthy immune system during a lockdown to stop the spread of a Virus.

Because healthy immune systems are no longer being exposed to other contacts, interactions and other environments. Also stress and loneliness during a lockdown might also be affecting the immune system.

Recovery from Coronavirus seems mainly dependent on our own immune system's ability to fight a virus.

Mark

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Re: Intrathecal antibody test
« Reply #8 on: Wednesday 20 May 20 20:45 BST (UK) »
I really think to send small children back to school is wrong, even though seemingly most get mild symptoms ,but can they transmit the disease and what if they get the very rare but severe complications?
Bury Council are not sending them back.
It is also interesting re our immune systems,like children who never mixed with their peers  got every illness going when the eventually did.
Viktoria.