Hi Juliette,
You can access a number of Dublin directories online:
Shaw's Dublin Directory 1850:
http://www.dublin1850.com/dublin1850/index.htmlDirectories for 1824, 1842 and 1846:
http://www.failteromhat.com/index.htmI had a look at the 1850 directory and found the following possibilities:
DOYLE
Anne, 34 Henry St (hosier)
Catherine, 225 Great Britain St (chandler)
Catherine, 21 Blackhall row (victualler)
John, 32 Lower Mount St (grocer)
John, 19 Upper Mecklenburgh St (occup not listed)
John, 58 Mary St (clothier)
John, 86 Lower Camden St (house smith)
John, 1 Dawson's circus (green grocer)
John, 24 East Essex St (tailor)
John, 15 Lower Summerhill (flour stores)
John, 3 Old Church St (provision dealer)
John, 25 Clarendon St (tailor)
Margaret, 24 Arran St East (straw bonnet maker) - but maybe your Margaret was too young to be mentioned in the 1850 directory?
There is no Anne Doyle mentioned in the 1842 directory so maybe her husband was still alive then? The only Doyle living in Henry Street in 1842 was William Doyle, house painter (2 Henry Street).
The 1846 directory lists Ann Doyle under Hosiers at 36 Henry Street. William Doyle still at 2 Henry Street in 1842 so I guess that rules him out as a possible husband.
Well, I don't know if any of this helps but hopefully you'll manage to gain something useful from one of the directories. Good luck with your research!
Best wishes,
Kirsten