Most hearty thanks to both of you, Kris and Deb, for your diligence on my behalf! It's incredibly exciting to see so many possibilities in an area I had all but given up on. I've not sent for a marriage cert yet because I'm not entirely sure I'm on the right track, but I did contact Tony Clark on the website that Kris provided. Still waiting for a reply.
I am sure all the Fluellens (and variant spellings) are connected somehow. But the Anne Conant Fluellen I am looking for was born around 1830 and was married to John Drew, a blacksmith, in 1850, so the 1822 marriage to Samuel doesn't look like the right one to me, unless I've got the birth year wrong and the marriage to John is a perhaps a second marriage?
John Drew and Anne Fluellen had a daughter, Mary Ann Drew in 1854 (who married Edward Benwell in 1874). If the Samuel = Anne 1822 marriage is my Anne, that would make her pretty long in the tooth when she had Mary Ann.
At this point, I'm as confused as I am excited. But thank you both, again. I really am so grateful for your efforts and your input.
~griphynne