Hi Sandra
I've just had q quick look at the other people you mention in your post
In my FT, I have a marriage between a Hannah Bartholomew and a John Higgleton in Sep 1859, but this Hannah is the daughter of Robert Bartholomew and Susan Purkis, ch Sep 16 1827 in White Colne.
John was a widower, having previously been married to Lydia Pitchford and having 8 children - which fits with there being 3 children in the 1861 Census - all from the first marriage. Robert and Susan had a total of 11 children, but not one named Matilda.
However FreeReg does have a Matilda Bartholomew ch Oct 28 1855 in White Colne to Parents Joesph and Hannah - so you are right about one of Amelia's sisters
With regard to Florence Emma Clayden - her mother's maiden name was Stokes according to the GRO and there is a Clayden/Stokes marriage in 1874 in St Pancras. I can't find a 1881 census record with Florence and Hannah Bartholomew (or Higgleton) in the same family.
With regard to the Clayden/Bartholomew marriage in 1899 in Romford, I note there was another Amelia Bartholomew b in 1877 in West Ham. She would have been 22 in 1899, but you would need to get the marriage certificate to confirm her age.
The Bartholomew family can be a bit of a nightmare to research, as I've found to my cost, but I hope this clears up a few anomalies for you
Tony P