Good evening,
This a new experience for me. I am a bit confused by your most recent post. Am I to understand that you have matched a proven individual from the Henrietta Howe line? This is very important for me, as well as for my family, as I was recently diagnosed with Porphyria. The type of Porphyria is the same as Prince William (see:
https://en.wikipedia.org/wiki/Prince_William,_Duke_of_Gloucester) who was diagnosed with it in his lifetime.
If indeed, you matched the Howe associated with lineage that goes back to Mary Queen of Scots and the German Houses associated with King George and Prince William, then an explanation regarding my illness may come into view. My hematologist and the geneticist say that I was a carrier, as was my mother, until an insult to my body activated the condition. I now cannot be in the sun or fluorescent light. They also told me the condition can be dormant for generations. In my case, it was a chemical that triggered its appearance. My reaction to the increased porphyrins is characterized by blisters on my skin that appear after sun exposure. My skin also burns from sun exposure. I have neurological involvement as well and if I do not get to a hospital when I am suffering an attack, there are grave consequences. Everything from an inability to ambulate to loss of sight and respiratory arrest. If all goes well, these conditions do pass after infusions but unfortunately some can linger for weeks to months. The insult to my body left me chronically porphyric. If there are others on this board who have a similar condition, I would like to know of them.
I do not have any other line that would explain where Porphyria might come down to me. My mother is a direct descendant of Joseph Howe of Virginia through Ann,his daughter, who married Robert Alexander Paris/Parris/Pearis and they settled in Shelby County, Kentucky. I have urged so many of my cousins to have their DNA done and many of us are participating in Gedmatch. We would like to participate in your Gedmatch exercise but do not feel comfortable posting our results publicly.
So glad you got someone in the Howe family in England to cooperate. For me, it can help to answer a health mystery that I had assumed could have come through the Howe line, but when I read your post tonight indicating you had matched a descendant of Henrietta, I feel we have made great progress.
Hoping to hear from you soon,
Shay McNeal
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